Catalogue number: I666660
Chemical name: Intermedine
Synonyms: (2S,3R)-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid [(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl Ester; [1R-[1α,7(2S*,3R*),7aβ]]-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl Ester; (+)-Intermedine
CAS Number: 10285-06-0
Possible CAS #: NA
Molecular form.: C₁₅H₂₅NO₅
Appearance: Off-White Low Melting Solid
Melting Point: >33°C (dec.)
Mol. Weight: 299.36
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Culvenor, C., et al.: J. Agr. Food Chem., 29 958 (1981); Janes, D., et al.: Nat. Prod. Comm., 7, 861 (2012); Li, Y. & Stermitz, F.: J. Nat. Prod., 51, 1289 (1988); McCulloch, E.: Am. Vet. Med. Assoc., 96, 5 (1940); Pawar, R., et al.: J. Sep. Sci., 33, 200 (2010)
Peer Review Product Citations:

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  Pack size Price(USD)
.5mg $225.00
  Pack size Price(USD)
5mg $1800.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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