Indicine N-Oxide

Catalogue number: I521105
Chemical name: Indicine N-Oxide
Synonyms: (2R,3S)-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid [(1R,7aS)-2,3,5,7a-Tetrahydro-1-hydroxy-4-oxido-1H-pyrrolizin-7-yl]methyl Ester; [1R-[1α,7(2R*,3S*),7aβ]]-2,3-Dihydroxy-2-(1-methylethyl)butanoic Acid (2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl Ester N-Oxide; (+)-Indicine N-oxide; NSC 132319
CAS Number: 41708-76-3
Possible CAS #: NA
Molecular form.: C₁₅H₂₅NO₆
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 315.36
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Apoptosis, Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Indicine N-oxide is a pyrrolizidine alkaloid that is isolated from Heliotropium indicum, one of the most widely used herbs in India. Indicine N-oxide exhibits antitumour and antimitotic activity in humans, and has subsequently undergone Phase I & II trials in adults and children with leukemia and solid tumours.
Dangerous Goods Info: NA
References: Kovach, J., et al.: Cancer Res., 39, 4540 (1979); Powis, G., et al.: Cancer Res., 39, 3564 (1979); Whitehead, V., et al.: Cancer Chemo. Pharma., 26, 377 (1990)
Peer Review Product Citations:

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