Catalogue number: I387525
Chemical name: 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline
CAS Number: 943320-48-7
Possible CAS #: NA
Molecular form.: C₁₀H₈F₃N₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 227.19
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 3-(1H-Imidazol-1-yl)-5-(trifluoromethyl)-aniline is a reactant used in the synthesis of novel Bcr/Abl inhibitors as anti-cancer drugs. Nilotinib (N465300) impurity, which might be useful in treatment of chronic myelogenous leukemia.
References: Wang, D. et al.: Bioorg. Med. Chem. Lett., 21, 1965 (2011); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),
Dangerous Goods Info: NA

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