IMD 0354

Catalogue number: I268650
Chemical name: IMD 0354
Synonyms: N-(3,5-Bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxy-benzamide; 5-Chloro-α,α,α,α’,α’,α’-hexafluoro-3’,5’-salicyloxylidide N-(3,5-Bis(trifluoromethyl)phenyl)-5-chloro-2-hydroxybenzamide
CAS Number: 978-62-1
Possible CAS #: NA
Molecular form.: C₁₅H₈ClF₆NO₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 383.67
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Inhibitors
Boiling Point: No Data Available
Applications: IMD 0354 is an inhibitor of IKK β (IKK-2) and blocks Iκβα phosphorylation in the NF-κB pathway. IMD 0354 might also have therapeutic efficacy in the treatment of human mesothelioma.
Dangerous Goods Info: NA
References: Nishikawa, S., et al.: Cancer Med., 3, 416 (2014); Tanka., A., et al.: Blood, 105, 2324 (2005); Sugita. A., et al.: Int. Arch. Allergy Immunol, 148, 186 (2009); Kamon, J.M., et al.:Biochem., Biophys, Res. Commun,, 323, 242 (2004); Onai, et al.: Cardiovasc. Res., 63, 51 (2004)
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $65.00
50mg $395.00
  Pack size Price(USD)
10mg $90.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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