Iloprost

Catalogue number: I267300
Chemical name: Iloprost
Synonyms: (5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-yn-1-yl]-2(1H)-pentalenylidene]pentanoic Acid; (1S,2R,3R,5S)-7-[(E)-4-Carboxybutylidene]-2-[(3S,1E)-3-hydroxy-4-methyl-6-octyn-1-enyl]-bicyclo[3.3.0]octane; Ciloprost; Endoprost; Ilomedin; ZK 36374;
CAS Number: 78919-13-8
Possible CAS #: NA
Molecular form.: C₂₂H₃₂O₄
Appearance: Colourless Oil to Off-White Stick Solid
Melting Point: N/A
Mol. Weight: 360.49
Storage: Amber Vial, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly)
Stability: Light and Temperature Sensitive
Category: Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud’s phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References:
Peer Review Product Citations:

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  Pack size Price(USD)
500µg $95.00
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2.5mg $420.00
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10mg $1350.00
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  Pack size Price(USD)
1mg $175.00
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5mg $800.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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