IDRA-21

Catalogue number: I232500
Chemical name: IDRA-21
Synonyms: 7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-Dioxide;
CAS Number: 22503-72-6
Possible CAS #: NA
Molecular form.: C₈H₉ClN₂O₂S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 232.69
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: IDRA-21 is a benzothiadiazine derivative and a positive allosteric modulator of glutamate AMPA receptors (1,2,3,4). It is able to increase excitatory synaptic strength by inhibiting AMPA receptor desensitization. IDRA 21 may exhibit therapeutic effects to ameliorate memory deficits in patients with cognitive impairments such as Alzheimer’s disease.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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