Catalogue number: H998002
Chemical name: Hymenialdisine-d4
Synonyms: (4Z)-4-(2-Amino-1,5-dihydro-5-oxo-4H-imidazol-4-ylidene)-2-bromo-4,5,6,7 -tetrahydro-pyrrolo[2,3-c]azepin-8(1H)-one-d4; (Z)-Hymenialdisine-d4;
CAS Number: 1185240-30-5
Possible CAS #: unlabelled: 82005-12-7
Molecular form.: C₁₁H₆D₄BrN₅O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 328.16
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Isotope Labelled Compounds, Protein Kinase Inhibitors and Activators, Tyrosine Kinase Inhibitors
Boiling Point: No Data Available
Applications: A potent inhibitor of a variety of kinases including MEK-1, GSK-3Β, and CKI. It also exhibits inhibition of the G2 cell cycle checkpoint at the micromolar concentrations. A marine sponge alkaloid, a natural product.
Dangerous Goods Info: NA
References: Cheetham, G., et al.: J. Biol. Chem., 277, 42419 (2002), Bain, J., et al.: Biochem. J., 371, 199 (2003), Sharma, V., et al.: Bioorg. Med. Chem. Lett., 14, 4319 (2004), Anamika, et al.: Proteins, 58, 180 (2005), Birault, V., et al.: Curr. Med. Chem., 13, 1735 (2006),
Peer Review Product Citations:

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