4-Hydroxy-Teriflunomide

Catalogue number: H956180
Chemical name: 4-Hydroxy-Teriflunomide
Synonyms: (2Z)-2-Cyano-3,4-dihydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide
CAS Number: 1058722-45-4
Possible CAS #: NA
Molecular form.: C₁₂H₉F₃N₂O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 286.21
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Inhibitors,
Boiling Point: No Data Available
Applications: 4-Hydroxy-Teriflunomide is a metabolite of Leflunomide (L322750), an immunosuppressive. Inhibits T and B cell proliferation. Activity is attributed mainly to its metabolite, a malononitrile derivative, which is beleived to inhibit dihydroorotate dehydrogenase as well as several protein tyrosine kinases. Therapeutically as a antirheumatic (Merck Index).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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