5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)

Catalogue number: H954455
Chemical name: 5-Hydroxy Topotecan Dihydrochloride (Mixture of Diastereomers)
Synonyms: (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9,12-trihydroxy-1H-Pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Dihydrochloride Salt; 10-Hydroxy-9-[(dimethylamino)methyl]-5-hydroxy-(20S,5RS)-camptothecin Dihydrochloride Salt
CAS Number: 504413-73-4
Possible CAS #: NA
Molecular form.: C₂₃H₂₅Cl₂N₃O₆
Appearance: Orange Solid
Melting Point: >168°C (dec.)
Mol. Weight: 510.37
Storage: Hygroscopic, Refrigerator, Under inert atmosphere
Solubility: Aqueous Acid (Slightly), DMSO (Slightly)
Stability: Hygroscopic
Category: Chiral Reagents, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Dihydrochloride Salt of 5-Hydroxy Topotecan, is the metabolite of Topotecan (T542500), which is a DNA topoisomerase I inhibitor, semi synthetic analog of Camptothecin, and an antineoplastic.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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