2-Hydroxy Nevirapine 2-O-β-D-Glucuronide

Catalogue number: H949955
Chemical name: 2-Hydroxy Nevirapine 2-O-β-D-Glucuronide
Synonyms: 11-Cyclopropyl-6,11-dihydro-4-methyl-6-oxo-5H-dipyrido[3,2-b:2’,3’-e][1,4]diazepin-2-yl β-D-Glucopyranosiduronic Acid
CAS Number: 245500-91-8
Possible CAS #: NA
Molecular form.: C₂₁H₂₂N₄O₈
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 458.42
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: 2-Hydroxy Nevirapine 2-O-β-D-Glucuronide is the O-glucuronide derivative of 2-Hydroxy Nevirapine (H948625); a metabolite of Nevirapine (N391275) which is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Also antiviral.
Dangerous Goods Info: NA
References: Hargrave, K.D., et al.: J. Med. Chem., 34, 2231 (1991); Cheeseman, S.H., et al.: Antimicrob. Agents Chemother., 37, 178 (1993); Guay, L.A., et al.: Lancet, 354, 795 (1999); Erickson, D.A., et al.: Drug Metab. Dispos., 27, 1488 (1999); Riska, P.S., et al.: Drug Metab. Dispos., 27, 1434 (1999)
Peer Review Product Citations:

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5mg $725.00
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10mg $1600.00
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