(6R)-Hydroxy (R,S)-Palonosetron

Catalogue number: H949455
Chemical name: (6R)-Hydroxy (R,S)-Palonosetron
Synonyms: [3aR-[2(S*),3aα,6α]]-2-(1-azabicyclo[2.2.2]oct-3-yl)-2,3,3a,4,5,6-hexahydro-6-hydroxy-1H-Benz[de]isoquinolin-1-one
CAS Number: 175873-26-4
Possible CAS #: NA
Molecular form.: C₁₉H₂₄N₂O₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 312.41
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: (6R)-Hydroxy (S,R)-Palonosetron is a stereoisomer of (6S)-Hydroxy (S,S)-Palonosetron (H949365). (6S)-Hydroxy (S,S)-Palonosetron (H949365) is a metabolite of Palonosetron (P165800, HCl salt) which is a potent, single stereoisomeric 5-HT3 receptor antagonist developed to prevent chemotherapy-induced nausea and vomiting.
Dangerous Goods Info: NA
References: Stoltz, R., et al.: Biopharm. Drug Dispos., 25, 329 (2004)
Peer Review Product Citations:

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