Catalogue number: H946620
Chemical name: (R)-N-(1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Synonyms: N-[(1R)-2-(3-Hydroxyisovaleryl)amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₉H₂₂N₄O₄
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 370.4
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (R)-N-(1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide is an impurity of Bortezomib (B675700); the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.
Dangerous Goods Info: NA
References: Nawrocki, S.T., et al.: Cancer Res., 65, 11510 (2005); Drahl, C.: Chem. and Eng. News, 87, 41 (2009)
Peer Review Product Citations:

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