N-(4-Hydroxymethylbenzyl) Cyclam

Catalogue number: H945945
Chemical name: N-(4-Hydroxymethylbenzyl) Cyclam
Synonyms: 4-(1,4,8,11-Tetraazacyclotetradec-1-ylmethyl)-Benzenemethanol; Plerixafor Impurity I;
CAS Number: 176252-20-3
Possible CAS #: NA
Molecular form.: C₁₈H₃₂N₄O
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 320.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: N-(4-Hydroxymethylbenzyl) Cyclam is an impurity of Plerixafor (P580500), a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α). This agent was approved on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in patients with non-Hodgkin’s lymphoma (NHL) and multiple myeloma (MM).
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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