3-Hydroxyhexadecanoylcarnitine Inner Salt (Mixture of Diastereomers)

Catalogue number: H943005
Chemical name: 3-Hydroxyhexadecanoylcarnitine Inner Salt (Mixture of Diastereomers)
Synonyms: 3-Hydroxypalmitoylcarnitine; (2R)-3-Carboxy-2-[(3-hydroxy-1-oxohexadecyl)oxy]-N,N,N-trimethyl-1-propanaminiumInner Salt, [1(R)]-3-Carboxy-2-[(3-hydroxy-1-oxohexadecyl)oxy]-N,N,N-trimethyl-1-propanaminium Inner Salt;
CAS Number: 195207-76-2
Possible CAS #: NA
Molecular form.: C₂₃H₄₅NO₅
Appearance: White to Off-White Solid
Melting Point: >97°C (Subl.)
Mol. Weight: 415.61
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Sparingly), Methanol
Stability: Hygroscopic
Category: Aliphatics, Amino Acids & Derivatives, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 3-Hydroxyhexadecanoylcarnitine Inner Salt is a derivative of Carnitine, essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthetized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado. Also 3-Hydroxyhexadecanoylcarnitine works similar to the endogenous non-toxic molecule L-Carnitine (C184110) whose bioavailablity is improved due to the transport systems in place for Carnitine.
Dangerous Goods Info: NA
References: Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978), Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001), Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004), O. Piermatti. et al.: Bioorg. Med. Chem., 16, 1444 (2008);
Peer Review Product Citations:

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