4-Hydroxy Estrone 1-N7-Guanine

Catalogue number: H942120
Chemical name: 4-Hydroxy Estrone 1-N7-Guanine
Synonyms: 2-Amino-7-(3,4-dihydroxy-17-oxoestra-1,3,5(10)-trien-1-yl)-1,7-dihydro-6H-purin-6-one; 4-OH-E1-1-N7Gua;
CAS Number: 178971-92-1
Possible CAS #: NA
Molecular form.: C₂₃H₂₅N₅O₄
Appearance: Light Brown Solid
Melting Point: >260°C (dec.)
Mol. Weight: 435.48
Storage: Hygroscopic, Refrigerator, under inert atmosphere
Solubility: DMSO (Slightly)
Stability: No Data Available
Category: Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point: No Data Available
Applications: 4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.
Dangerous Goods Info: NA
References: Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $175.00
  Pack size Price(USD)
10mg $1400.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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