6-Hydroxy Dopamine-d4 Hydrobromide

Catalogue number: H941732
Chemical name: 6-Hydroxy Dopamine-d4 Hydrobromide
Synonyms: 2,4,5-Trihydroxyphenethylamine-d3 Hydrobromide; 5-(2-Aminoethyl)-1,2,4-benzenetriol-d3 Hydrobromide; 6-Hydroxydopamine-d3 Hydrobromide; Oxidopamine-d3 Hydrobromide; Topamine-d3 Hydrobromide;
CAS Number: NA
Possible CAS #: unlabelled: 636-00-0
Molecular form.: C₈H₈D₄BrNO₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 254.11
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Isotope Labelled Compounds, Neurochemicals, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Labelled 6-Hydroxydopamine, a selective catecholaminergic neurotoxin. Studies show that 6-Hydroxydopamine can be used to create an animal model of Parkinson’s disease as it causes almost complete destruction of nigral dopaminergic neurons and their striatal terminals when injected into the substantia nigra of rats. 6-Hydroxydopamine induces apoptosis in PC12 cells.
Dangerous Goods Info: NA
References: Soto-Otero, R. et al.: J. Neurochem., 74, 1605 (2000); Fujita, H. et al.: Brain Res., 1113, 10 (2006); Breese, G.R. et al.: 174, 313 (1970);
Peer Review Product Citations:

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