Catalogue number: H940080
Chemical name: 1-(4-Hydroxyphenyl)thiourea
Synonyms: N-(4-Hydroxyphenyl)thiourea; 1-(p-Hydroxyphenyl)-2-thiourea; 4-Hydroxyphenylthiourea; 4-Thioureidophenol; N-(4-Hydroxyphenyl)thiourea; NSC 43638; p-Hydroxyphenylthiourea
CAS Number: 1520-27-0
Possible CAS #: NA
Molecular form.: C₇H₈N₂OS
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 168.22
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: 1-(4-Hydroxyphenyl)thiourea is an intermediate in the synthesis of (SKI II), a nonlipid inhibitor of sphingosine kinase. SKI II s orally bioavailable and has shown significant inhibition of tumor growth in mice.
Dangerous Goods Info: NA
References: Sharma, A.K., et. al.: Eur. J. Med. Chem., 45, 4149 (2010); French, K.J., et. al.: Cancer Res., 63, 5962 (2003); French, K.J., et. al.: J. Pharmacol. Exp. Ther., 318, 596 (2006)
Peer Review Product Citations:

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