Catalogue number: H939800
Chemical name: 2-Hydroxyisoquinoline-1,3(2H,4H)-dione
Synonyms: 2-Hydroxy-1,3(2H,4H)-isoquinolinedione;
CAS Number: 6890-08-0
Possible CAS #: NA
Molecular form.: C₉H₇NO₃
Appearance: Brown Solid
Melting Point: 197-200°C
Mol. Weight: 177.16
Storage: Refrigerator
Solubility: DMSO
Stability: No Data Available
Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopic techniques and report that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent.
References: Greenwald, J., et al.: Biochemistry, 38, 8892 (1999), Tramontano, E., et al.: Antiviral Res., 65, 117 (2005), Schultz, S., et al.: Virus Res., 134, 86 (2008), Williams, P., et al.: Bioorg. Med. Chem. Lett., 22, 6754 (2010),
Dangerous Goods Info: NA

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50mg $110.00
250mg $350.00
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25mg $75.00
100mg $150.00
1g $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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