Hydroxy cyclophosphamide Semicarbazone

Catalogue number: H926305
Chemical name: Hydroxy cyclophosphamide Semicarbazone
Synonyms: N,N-bis(2-chloroethyl)phosphorodiamidic Acid 3-[2-(Aminocarbonyl)hydrazinylidene]propyl Ester; NSC 319519; Aldophosphamide Semicarbazone
CAS Number: 53948-46-2
Possible CAS #: NA
Molecular form.: C₈H₁₈Cl₂N₅O₃P
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 334.14
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Metabolites, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Aldophosphamide semicarbazone is a major metabolite of cyclophosphamide (C988580), a cytotoxic nitrogen mustard derivative widely used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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