Hydroxy Bosentan

Catalogue number: H830270
Chemical name: Hydroxy Bosentan
Synonyms: 4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2’-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634; Ro 48-5033
CAS Number: 253688-60-7
Possible CAS #: NA
Molecular form.: C₂₇H₂₉N₅O₇S
Appearance: White Solid
Melting Point: 128-132°C
Mol. Weight: 567.61
Storage: -20°C Freezer, Under Inert Atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Aromatics, Heterocycles, Metabolites & Impurities, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: The active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
Dangerous Goods Info: NA
References: Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $175.00
5mg $735.00
25mg $1500.00
  Pack size Price(USD)
2mg $325.00
10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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