4-Hydroxy Atorvastatin-d5 Disodium Salt

Catalogue number: H828962
Chemical name: 4-Hydroxy Atorvastatin-d5 Disodium Salt
Synonyms: (βR,δR)-2-(4-Fluorophenyl)-β,δ-dihydroxy-4-[[(4-hydroxyphenyl)amino]carbonyl]-5-(1-methylethyl)-3-phenyl-1H-pyrrole-1-heptanoic Acid Disodium Salt; BMS 241423-01; PD 142542; p-Hydroxyatorvastatin;
CAS Number: NA
Possible CAS #: unlabelled: 1276537-18-8
Molecular form.: C₃₃H₂₈D₅FN₂Na₂O₆
Appearance: Brown Solid
Melting Point: >166°C (dec.)
Mol. Weight: 623.63
Storage: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility: Methanol, Water
Stability: Hygroscopic
Category: Aromatics, Chiral Reagents, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: A deuterated metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Dangerous Goods Info: NA
References: Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),
Peer Review Product Citations:

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10mg $1800.00
Exact Weight Packaging ($75(USD) / Vial)
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