Catalogue number: H825555
Chemical name: 3-Hydroxy-2,2-dimethylpropanal
Synonyms: 2,2-Dimethyl-3-hydroxypropanal; 2,2-Dimethyl-3-hydroxypropionaldehyde; 2-(Hydroxymethyl)-2-methylpropanal; 2-(Hydroxymethyl)isobutyraldehyde; 3-Hydroxy-2,2-dimethylpropionaldehyde; 3-Hydroxypivalaldehyde; Hydroxypivalaldehyde; Hydroxypivaldehyde; Pentaaldol; Pentaldol; α,α-Dimethyl-β-hydroxypropionaldehyde
CAS Number: 597-31-9
Possible CAS #: NA
Molecular form.: C₅H₁₀O₂
Appearance: White Solid
Melting Point: 102-105°C
Mol. Weight: 102.13
Storage: Refrigerator
Solubility: Chloroform, DMSO, Methanol, Water (Slightly)
Stability: No Data Available
Category: Miscellaneous Reagents
Boiling Point: No Data Available
Applications: 3-Hydroxy-2,2-dimethylpropanal is used to prepare 4,1-benzoxazepines as squalene synthase inhibitors and their inhibition of cholesterol synthesis. It is also used to prepare chiral cyanohydrins.
Dangerous Goods Info: NA
References: Miki, T., et al.: J. Med. Chem., 45, 4571 (2002); Ognyanov, V., et al.: J. Am. Chem. Soc., 113, 6992 (1991)
Peer Review Product Citations:

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