12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid-d4

Catalogue number: H825287
Chemical name: 12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid-d4
Synonyms: [S-(E,Z,Z,Z)]-12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-HETE-d4; 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4; 12-Hydroxyeicosatetraenoic Acid-d4; 12-L-Hydroxy-5,8,10,14-eicosatetraenoic Acid-d4;
CAS Number: NA
Possible CAS #: Unlabelled: 54397-83-0
Molecular form.: C₂₀H₂₈D₄O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 324.49
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aliphatics, Glycerols, Fatty Acid Derivatives & Lipids, Isotope Labelled Compounds, Metabolites & Impurities
Boiling Point: No Data Available
Applications: A labelled fatty acid metabolite of arachidonic acid (A765000). Potential biomarker for asthma monitoring and diagnosis. Stimulates protein kinase C-mediated release of cathepsin B from malignant cells. Used in the study of mechanisms controlling cell cycle arrest and induction of apoptosis in prostate cancer cells via 12-lipoxygenase inhibition.
Dangerous Goods Info: NA
References: Nording, M.L. et al.: IEEE Sensors J., 10, 123 (2010); Pidgeon, G.P. et al.: Canc. Res., 62, 2721 (2002); Honn, K.V. et al.: Exp. Cell Res., 214, 120 (1994); Feldstein, A.E. et al.: J. Lipid Res., 51, 3046 (2010);
Peer Review Product Citations:

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