HX 630

Catalogue number: H674250
Chemical name: HX 630
Synonyms: 4-(7,8,9,10-tetrahydro-7,7,10,10-tetramethylbenzo[b]naphtho[2,3-f][1,4]thiazepin-12-yl)benzoic Acid;
CAS Number: 188844-52-2
Possible CAS #: NA
Molecular form.: C₂₈H₂₇NO₂S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 441.58
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Agonist, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: A nuclear receptor retinoid X receptor (RXR) agonist that exerts antiproliferative effects in vascular smooth muscle cells (VSMCs) in vivo and in vitro. A potential therapeutic target for vascular injury and intimal thickening. It efficiently enhanced ABCA1 mRNA expression and apoA-I-dependent cellular cholesterol release in differentiated THP-1 cells.
Dangerous Goods Info: NA
References: Haraguchi, G. et al.: J. Mol. Cell. Cardiol., 41, 885 (2006); Nishimaki-M. et al.: Biochem. Pharmacol., 76, 1006 (2008);
Peer Review Product Citations:

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