(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester

Catalogue number: H656560
Chemical name: (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
Synonyms: (2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester; 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S-trans)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid Methyl Ester; (2S,4R)-1-Boc-4-hydroxy-L-proline Methyl Ester; Methyl (4R)-N-Boc-4-hydroxy-L-prolinate; N-tert-Butoxycarbonyl-L-hydroxyproline Methyl Ester;
CAS Number: 74844-91-0
Possible CAS #: NA
Molecular form.: C₁₁H₁₉NO₅
Appearance: Clear Colourless Oil
Melting Point: N/A
Mol. Weight: 245.27
Storage: Refrigerator
Solubility: Chloroform, Dichloromethane, DMF, Ethyl Acetate
Stability: No Data Available
Category: Amino Acids & Derivatives, Chiral Reagents, Heterocycles
Boiling Point: No Data Available
Applications: (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.
Dangerous Goods Info: NA
References: Freer, R., et al.: Biochemistry, 21, 257 (1982), Higgins, J., et al.: J. Med. Chem., 39, 1013 (1996), Cavicchioni, G., et al.; Bioorg. Chem., 34, 298 (2006), Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (2006),
Peer Review Product Citations:

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Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Pending QC

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