HMN 214

Catalogue number: H456360
Chemical name: HMN 214
Synonyms: (E)-N-[(4-Methoxyphenyl)sulfonyl]-N-[2-[2-(1-oxido-4-pyridinyl)ethenyl]phenyl]-acetamide; (E)-4-[2-[2-[N-Acetyl-N-[(p-methoxyphenyl)sulfonyl]amino]phenyl]ethenyl]pyridine 1-Oxide; IVX 214
CAS Number: 173529-46-9
Possible CAS #: NA
Molecular form.: C₂₂H₂₀N₂O₅S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 424.47
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: HMN 214 is a novel oral stilbene derivative with polo-like kinase-1-interacting properties, in patients with advanced solid tumors. It is a prodrug of HMN 176, a stilbene derivative that interferes with the subcellular spatial location of polo-like kinase-1 (PLK1).
Dangerous Goods Info: NA
References: Garland, L., et al.: Clin. Cancer Res., 12, 5182 (2006)
Peer Review Product Citations:

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