Catalogue number: H296530
Chemical name: (3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone
Synonyms: [3S-[3α,4β(S*)]]-3-Hexyl-4-(2-hydroxytridecyl)-2-oxetanone;
CAS Number: 104872-06-2
Possible CAS #: NA
Molecular form.: C₂₂H₄₂O₃
Appearance: White to Off-White Solid
Melting Point: 48-51ºC
Mol. Weight: 354.57
Storage: No Data Available
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Drug Analogues, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: (3S,4S)-3-Hexyl-4-[(2R)-2-hydroxytridecyl]-2-oxetanone is an analog of Tetrahydrolipstatin, an inhibitor of the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG), also an intermediate in the preparation of Orlistat (O686500).
Dangerous Goods Info: NA
References: Mechoulam, R., et al.: Biochem. Pharmacol., 50, 83 (1995), Bisogno, T., et al.: J. Cell Biol., 163, 463 (2003), Di Marzo, V., et al.: Nat. Rev. Drug Discovery, 7, 438 (2008), Ortar, G., et al.: J. Med. Chem., 51, 6970 (2008),
Peer Review Product Citations:

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