HA 150

Catalogue number: H011600
Chemical name: HA 150
Synonyms: B-[3-[[4-[[3-[(4-Fluorophenyl)methyl]-2,4-dioxo-5-thiazolidinylidene]methyl]phenoxy]methyl]phenyl]boronic Acid;
CAS Number: 1229652-21-4
Possible CAS #: NA
Molecular form.: C₂₄H₁₉BFNO₅S
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 463.29
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Aromatics, Boron Derivatives, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: HA 150 is a selective boronic acid-based inhibitor of autotaxin. Studies show that adminstration of HA 150 in mice results in rapid decrease of the lipid mediator lysophosphatidic acid (LPA) in the circulation. These findings suggest that HA 150 may provide useful therapeutic strategy in treating disorders associated with vascular development, inflammation, fibrotic disease, and tumor progression.
References: Albers, H.M.H.G. et al.: Proc. Natl. Acad Sci. USA, 107, 7257 (2010); Albers, H.M.H.G. et al.: J. Med. Chem., 53, 4958 (2010);
Dangerous Goods Info: NA

Order Product

  Pack size Price(USD)
25mg $150.00
  Pack size Price(USD)
250mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
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