GW 501516

Catalogue number: G931500
Chemical name: GW 501516
Synonyms: 2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid; Methyl-methyl-trifluoromethylphenyl -thiazolyl-methylsulfanyl-phenoxy-acetic Acid; GW 1516
CAS Number: 317318-70-0
Possible CAS #: NA
Molecular form.: C₂₁H₁₈F₃NO₃S₂
Appearance: White to Pale Yellow Solid
Melting Point: 134-144°C
Mol. Weight: 453.5
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds,
Boiling Point: No Data Available
Applications: An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream. A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα and PPARγ. Does not exibit any activity against other nuclear or non-nuclear receptors. Reported to increase cholesterol efflux and ABAC1 expression in macrophages, fibroblasts, and intestinal cells.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $45.00
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25mg $150.00
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250mg $475.00
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  Pack size Price(USD)
5mg $65.00
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50mg $250.00
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1g $675.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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