Genistein 7-Sulfate Sodium Salt

Catalogue number: G350045
Chemical name: Genistein 7-Sulfate Sodium Salt
Synonyms: 5-Hydroxy-3-(4-hydroxyphenyl)-7-(sulfooxy)-4H-1-benzopyran-4-one Sodium Salt
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₁₅H₉NaO₈S
Appearance: Off-White to Pale Beige Solid
Melting Point: >200°C (dec.)
Mol. Weight: 372.28
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Sparingly), Water
Stability: No Data Available
Category: Inhibitors, Tyrosine Kinase Inhibitors
Boiling Point: No Data Available
Applications: Genistein 7-Sulfate Sodium Salt is a derivative of Genistein (446-72-0). Genistein exhibits specific inhibitory activity against tyrosine kinases,including autophosphorylation of epidermal growth factor receptor kinase (IC50 - 2.6uM). Also inhibits other protein kinases through competitive inhibition of ATP. Inhibits tumor cell proliferation and induces tumor cell differentiation. Produces cell-cycle arrest and apoptosis in Jurat T-leukemia cells. However, it prevents anti-CD3 monoclonal antibody-induced thymic apoptosis. Genistein also inhibits topoisomerase II activity in vitro. Genistein has also been shown to inhibit the action of GABA on recombinant GABAA receptors 2. uv(max)ethanol: 262.5 nm (e= 138). moderately sol. in hot alcohol.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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  Pack size Price(USD)
2.5mg $150.00
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  Pack size Price(USD)
25mg $1200.00
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Exact Weight Packaging ($75(USD) / Vial)
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Inventory Status:   In Stock

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