Catalogue number: G245100
Chemical name: GANT61
Synonyms: 2,2’-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine; NSC 136476
CAS Number: 500579-04-4
Possible CAS #: NA
Molecular form.: C₂₇H₃₅N₅
Appearance: White to Off-White Solid
Melting Point: 110-113°C
Mol. Weight: 429.6
Storage: Refrigerator
Solubility: Chloroform, Methanol
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: GANT61 is an inhibitor for GLI1 as well as GLI2-induced transcription, inhibits hedgehog, displays selectivity over other pathways, such as TNF and glucocorticoid receptor gene transactivation.
Dangerous Goods Info: NA
References: Lauth, M., et al.: Proc. Natl. Acad. Sci., 104, 8455 (2007); Desch, P., et al.: Oncogene, 29, 4885 (2010); Mazumdar, Y., et al.: Cancer Res., 71, 1092 (2011)
Peer Review Product Citations:

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  Pack size Price(USD)
5mg $60.00
25mg $245.00
100mg $880.00
  Pack size Price(USD)
10mg $110.00
50mg $465.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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