Fursultiamine Hydrochloride

Catalogue number: F865230
Chemical name: Fursultiamine Hydrochloride
Synonyms: N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[(tetrahydrofurfuryl)dithio]-1-butenyl]-formamide Monohydrochloride; N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]-N-[4-hydroxy-1-methyl-2-[[(tetrahydro-2-furanyl)methyl]dithio]-1-butenyl]-formamide Monohydrochloride; Fursultiamine Hydrochloride; TTFD Hydrochloride; Thiamin Tetrahydrofurfuryl Disulfide Hydrochloride; Thiamine Tetrahydrofurfuryl Disulfide Hydrochloride
CAS Number: 2105-43-3
Possible CAS #: 804-30-8 free amine
Molecular form.: C₁₇H₂₇ClN₄O₃S₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 435
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Fursultiamine was synthesized for the purpose of developing forms of thiamine with improved lipophilicity for treating vitamin B1 deficiency. In addition to its clinical indication of avitaminosis, fursultiamine has been studied in clinical trials for Alzheimer’s disease and autistic spectrum disorders with positive but modest benefits. It has also been investigated in improving energy metabolism during exercise and reducing exercise-induced fatigue with conflicting results.
Dangerous Goods Info: NA
References: Miura, S.: Nippon Ganka Gakkai Zasshi, 69, 792 (1965); Mimori, Y., et al.: Met. Brain Disease, 11, 89 (1996); Webster, M., et al.: Eur. J. Appl. Physiol. Occup. Physio., 75, 520 (1997)
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