6-(4-Fluorophenyl)-3-morpholinone

Catalogue number: F595665
Chemical name: 6-(4-Fluorophenyl)-3-morpholinone
Synonyms:
CAS Number: 951626-54-3
Possible CAS #: NA
Molecular form.: C₁₀H₁₀FNO₂
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 195.19
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: 6-(4-Fluorophenyl)-3-morpholinone is a reagent that is used in the synthesis of Aprepitant (A729800), which is a novel selective neurokinin-1 (NK-1) receptor antagonist. In vitro studies using human liver microsomes indicate that Aprepitant is metabolised primarily by CYP3A4 with minor metabolism by CYP1A2 and CYP2C19, and no metabolism by CYP2D6, CYP2C9, or CYP2E1. Antiemetic.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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