Catalogue number: F593182
Chemical name: 4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide
CAS Number: NA
Possible CAS #: Unlabelled CAS# N/A
Molecular form.: C₂₀H₁₅D₃FN₅O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 398.41
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds
Boiling Point: No Data Available
Applications: 4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide is the labeled analogue of 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide (F593180), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
Dangerous Goods Info: NA
References: Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)
Peer Review Product Citations: Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)

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