4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide

Catalogue number: F593182
Chemical name: 4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide
Synonyms:
CAS Number: NA
Possible CAS #: NA
Molecular form.: C₂₀H₁₅D₃FN₅O₃
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 398.41
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Amines, Aromatics, Heterocycles, Impurities, Isotope Labelled Compounds
Boiling Point: No Data Available
Applications: 4-(3-Fluoro-4-((2-(methyl-d3-carbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide is the labeled analogue of 4-(3-Fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)amino)phenoxy)-N-methylpicolinamide (F593180), an impurity of Regorafenib (R143000), which inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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