9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one

Catalogue number: F591800
Chemical name: 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one
Synonyms: (2’R,8S,9R,10S,11S,13S,14S,16S)-4’-chloro-5’-ethyl-9-fluoro-11-hydroxy-10,13,16-trimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-3’H-spiro[cyclopenta[a]phenanthrene-17,2’-furan]-3,3’(6H)-dione; USP Clobetasol Propionate Related Compound A
CAS Number: 1486466-31-2
Possible CAS #: NA
Molecular form.: C₂₅H₃₀ClFO₄
Appearance: White to Off-White Solid
Melting Point: >280°C (dec.)
Mol. Weight: 448.95
Storage: Refrigerator
Solubility: Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
Boiling Point: No Data Available
Applications: 9α-Fluoro-11β-hydroxy-16-β-methyl-3-oxoandrosta-1,4-diene-17(R)-spiro-2’-[4’-chloro-5’-ethylfuran-3’(2’H)-one is an impurity in the synthesis of Clobetasol 17-Propionate (C583500), a topical corticosteroid. Glucocorticoid; anti-inflammatory.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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