Fumaric Acid Monomethyl Ester

Catalogue number: F500390
Chemical name: Fumaric Acid Monomethyl Ester
Synonyms: (2E)-2-Butenedioic Acid 1-Methyl Ester; (E)-2-Butenedioic Acid Monomethyl Ester; Fumaric Acid Methyl Ester; Methyl Hydrogen Fumarate; Monomethyl Fumarate;
CAS Number: 2756-87-8
Possible CAS #: NA
Molecular form.: C₅H₆O₄
Appearance: Off-White Solid
Melting Point: 143-146°C
Mol. Weight: 130.1
Storage: Refrigerator
Solubility: Chloroform, DMSO, Methanol
Stability: No Data Available
Category: Aliphatics, Metabolites & Impruities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Fumaric acid monomethyl ester is one of the most bioactive anti-psoriatic fumaric acid ester metabolite. Fumaric acid monomethyl ester is potent nicotinic acid receptor agonist. Fumaric acid monomethyl ester has also been shown to selectively stimulate of T helper 2 cytokine response. It is also the active metabolite of Dimethyl Fumarate (D464965), a compound that is used as a treatment for the relapsing forms of multiple sclerosis and psoriasis.
Dangerous Goods Info: NA
References: de Jong, R. et al.: Eur. J. Immunol., 26, 2067 (1996); Litjens, N.H.R. et al.: Br. J. Dermatol., 154, 211 (2006); Schimrigk, S., et al.: Eur. J. Neurol., 13, 604 (2006); Tang, H. et al.: Biochem. Biophys. Res. Comm., 375, 562 (2008)
Peer Review Product Citations:

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  Pack size Price(USD)
50mg $45.00
20g $125.00
50g $300.00
  Pack size Price(USD)
10g $75.00
25g $150.00
200g $575.00
Exact Weight Packaging ($75(USD) / Vial)
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