FK-506 (Tacrolimus)

Catalogue number: F370000
Chemical name: FK-506 (Tacrolimus)
Synonyms: Advagraf; FR 900506; Fujimycin; L 679934; Prograf; Protopic; TacroBell; Tacrolimus; Tsukubaenolide
CAS Number: 104987-11-3
Possible CAS #: NA
Molecular form.: C₄₄H₆₉NO₁₂
Appearance: White to Off-White Solid
Melting Point: >119°C (dec.)
Mol. Weight: 804.02
Storage: -20°C Freezer
Solubility: Chloroform (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: An immunosuppressant that blocks T cell proliferation in vitro by inhibiting the generation of several lymphokines, especially IL-2. Shown to inhibit the activity of FK-506 binding protein, thereby reversing its effects on sarcoplasmic reticulum Ca+2 release.
Dangerous Goods Info: Not a dangerous good if item is equal too or less than 1g/ml and there is less than 100g in the package
References: Asano, K., et al.: In Vivo, 10, 537 (1996), McCall, E., et al.: Circ. Res., 79, 1110 (1996), Raufman, J.P., et al.: J. Biol. Chem., 271, 19877 (1996), Rokaw, M.D., et al.: Am. J. Physiol., 271, C194 (1996), Knoll, G.A., and Bell, R.C.: Brit. Med. J., 318, 1104 (1999),
Peer Review Product Citations:

Order Product

  Pack size Price(USD)
5mg $50.00
50mg $85.00
250mg $290.00
  Pack size Price(USD)
10mg $55.00
100mg $165.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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