Fidaxomicin

Catalogue number: F335400
Chemical name: Fidaxomicin
Synonyms: (3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Clostomicin B1; Dificid; Dificlir; Fidaxomicin; Fidaxomycin; Lipiarmicin; Lipiarmycin; Lipiarmycin A 3; OPT 80; PAR 01; PAR 101; R-Tiacumicin B; Tiacumicin B
CAS Number: 873857-62-6
Possible CAS #: NA
Molecular form.: C₅₂H₇₄Cl₂O₁₈
Appearance: White Solid
Melting Point: >160°C (dec.)
Mol. Weight: 1058.04
Storage: Refrigerator
Solubility: DMSO, Methanol
Stability: No Data Available
Category: Aromatics, Chiral Reagents, Drug Analogues, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Fidaxomicin is a nonabsorbed macrocyclic antibiotic, and is the first antimicrobial to be approved by the FDA for the treatment of Clostridium difficile infection (CDI) in 20 years. Fidaxomicin works by inhibiting sporulation by CDI, sustaining clinical response and reducing recurrences of this pathogen.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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