Exenatide Acetate

Catalogue number: E957300
Chemical name: Exenatide Acetate
Synonyms: Exendin-4;
CAS Number: 141732-76-5
Possible CAS #: freebase: 141758-74-9
Molecular form.: C₁₈₄H₂₈₂N₅₀O₆₀S•C₂H₄O₂
Appearance: White to Off-White Solid
Melting Point: >209°C (dec.)
Mol. Weight: 4246.62
Storage: Refrigerator
Solubility: Acetonitrile (Slightly), Water (Slightly)
Stability: No Data Available
Category: Agonist, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A 39-amino acid peptide originally isolated from the salivary glands of the Gila monster (Heloderma suspectum), differs from exendin-3 only in two positions close to the N-terminus. Application of exenatide causes an increase in acinar cAMP without stimulating amylase release. As an incretin mimetic, exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor. As GLP-1, though with prolonged activity, exenatide augments the postprandial production of insulin and suppresses secretion of glucagon. For this reason, exenatide has found use as a medication of diabetes II.
Dangerous Goods Info: NA
References: Pugazhenthi, U. et al.: Diabetol., 53, 2357 (2010); Li, C. et al.: Bioche,. Biophys. Res. Comm., 400, 563 (2010); Lupi, R. et al.: Diab. Obes. Metab., 10, 515 (2008); Kim, T.H. et al.: Bioconj. Chem., 22, 625 (2011);
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $65.00
10mg $220.00
50mg $545.00
  Pack size Price(USD)
5mg $140.00
25mg $350.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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