Everolimus Retroaldol Degradation Product

Catalogue number: E945420
Chemical name: Everolimus Retroaldol Degradation Product
Synonyms: (S)-(2R,3S,6R,E)-1-((1S,3R,4R)-4-(2-Hydroxyethoxy)-3-methoxycyclohexyl)-2,6,8-trimethyl-5,9-dioxonon-7-en-3-yl 1-(2-((2R,3R,6S)-6-((2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxotrideca-3,5,7-trien-1-yl)-2-hydroxy-3-methyltetrahydro-2H-pyran-2-yl)-2-oxoacetyl)piperidine-2-carboxylate; Everolimus Ring-opening Impurity
CAS Number: 1708118-13-1
Possible CAS #: NA
Molecular form.: C₅₃H₈₃NO₁₄
Appearance: Off-White Solid
Melting Point: 45-50°C
Mol. Weight: 958.22
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: Everolimus Retroaldol Degradation Product is an impurity of Everolimus (E945400). Everolimus is a derivative of Rapamycin. Everolimus inhibits cytokine-mediated lymphocyte proliferation.
Dangerous Goods Info: NA
References: Dumont, F.J., et al.: Curr. Opin. Invest. Drugs, 2, 1220 (2001), Kovarik, J. M., et al.: Clin. Pharmacol. Ther., 69, 48 (2001), Nashan, B., et al.: Ther. Drug Monit., 24, 53 (2002),
Peer Review Product Citations:

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  Pack size Price(USD)
1mg $150.00
  Pack size Price(USD)
10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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