Catalogue number: E939010
Chemical name: Eurycomanone
Synonyms: 1,20-Epoxy-1,11,12,14,15-pentahydroxy-(1β,11β,12α,15β)-Picrasa-3,13(21)-diene-2,16-dione; NSC 339187; Pasakbumin A;
CAS Number: 84633-29-4
Possible CAS #: NA
Molecular form.: C₂₀H₂₄O₉
Appearance: Off-White Solid
Melting Point: N/A
Mol. Weight: 408.4
Storage: -20°C Freezer
Solubility: DMSO
Stability: No Data Available
Category: Apoptosis, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
Dangerous Goods Info: NA
References: Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);
Peer Review Product Citations:

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