Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate

Catalogue number: E907780
Chemical name: Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate
Synonyms: 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ethyl Ester; Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate; Febuxostat Ethyl Ester
CAS Number: 160844-75-7
Possible CAS #: NA
Molecular form.: C₁₈H₂₀N₂O₃S
Appearance: White to Off-White Solid
Melting Point: 174-176ºC
Mol. Weight: 344.43
Storage: Refrigerator
Solubility: DMSO (Slightly), Methanol (Very Slightly, Heated)
Stability: No Data Available
Category: Heterocycles, Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Ethyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methyl-5-thiazolecarboxylate is an impurity of Febuxostat (F229000), a xanthine oxidase/xanthine dehydrogenase inhibitor. Used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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