7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin (See E899155, HCl salt)

Catalogue number: E899150
Chemical name: 7-Ethyl-10-(4-amino-1-piperidino)carbonyloxycamptothecin (See E899155, HCl salt)
Synonyms: 4-Amino-(4S)-4,11-diethyl-3,4,12,14-tetrahydro -4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinolin-9-yl 1-Piperidinecarboxylic Acid Ester; RPR 132595A; NPC (metabolite);
CAS Number: 185304-42-1
Possible CAS #: NA
Molecular form.: C₂₈H₃₀N₄O₆
Appearance: Light Yellow to Yellow Solid
Melting Point: >160°C (dec.)
Mol. Weight: 518.56
Storage: Amber Vial, -86˚C Freezer, Under Inert Atmosphere
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: Moisture Sensitive
Category: Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: A major metabolite of Irinotecan.
Dangerous Goods Info: NA
References: Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),
Peer Review Product Citations:

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10mg $1200.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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