17α-Estradiol

Catalogue number: E887995
Chemical name: 17α-Estradiol
Synonyms: (17α)-Estra-1,3,5(10)-triene-3,17-diol; 1,3,5-Estratriene-3,17α-diol; 13β-Methyl-1,3,5(10)-gonatriene-3,17α-diol; 17-Epiestradiol; 17α-Oestradiol; 3,17-Dihydroxyestratriene; 3,17α-Dihydroxyoestra-1,3,5(10)-triene; Alfatradiol; Epiestrol; Estra-1,3,5(10)-triene-3,17α-diol; NSC 20293; α-Estradiol; Ethinyl Estradiol Impurity L (EP)
CAS Number: 57-91-0
Possible CAS #: NA
Molecular form.: C₁₈H₂₄O₂
Appearance: White to Off-White Solid
Melting Point: 210-219°C
Mol. Weight: 272.38
Storage: Refrigerator
Solubility: Dioxane (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals, Steroids,
Boiling Point: No Data Available
Applications: Estradiol (known as α-Estradiol or 17 α-Estradiol) is a biologically active estrogen in human breast cancer cells in tissue culture. 17-Εstradiol and its selective receptor, ER-X, are not part of a classical hormone/receptor endocrine system but of a system with important autocrine/paracrine functions in the developing and adult brain. 17-Estradiol may have enormous implications for hormone replacement strategies at the menopause and in the treatment of such neurodegenerative disorders as Alzheimer’s disease and ischemic stroke.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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