Catalogue number: E588680
Chemical name: 28-Epirapamycin
Synonyms: 28-epi-Rapamycin; (31S)-Rapamycin
CAS Number: 253431-35-5
Possible CAS #: NA
Molecular form.: C₅₁H₇₉NO₁₃
Appearance: Off-White Solid
Melting Point: >120°C (dec.)
Mol. Weight: 914.17
Storage: -20°C Freezer
Solubility: DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Chiral Reagents, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: 28-Epirapamycin is an epimer of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.
Dangerous Goods Info: NA
References: Yang, W., et. al.: Org. Lett., 1, 2033 (1999); Martel, P.R., et al.: Can. J. Physiol. Pharmacol., 55, 48 (1977); Carlson, R.P., et al.: J. Pharmacol. Exp. Ther., 266, 1125 (1993); Kahan, B.D., et al.: Lancet, 356, 194 (2000); Holmes, D.R., et al.: Circulation, 109, 634 (2004)
Peer Review Product Citations:

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  Pack size Price(USD)
2.5mg $175.00
  Pack size Price(USD)
25mg $1400.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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