5-epi Emtricitabine

Catalogue number: E524980
Chemical name: 5-epi Emtricitabine
Synonyms: 4-Amino-5-fluoro-1-[(2R,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (2R-trans)-4-Amino-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; 1,3-Oxathiolane, 2(1H)-Oyrimidinone Deriv.; α-L-FTC
CAS Number: 145986-26-1
Possible CAS #: NA
Molecular form.: C₈H₁₀FN₃O₃S
Appearance: Off-White Solid
Melting Point: >166°C (dec.)
Mol. Weight: 247.25
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Methanol, Water
Stability: No Data Available
Category: Amines, Aromatics, Chiral Reagents, Drug Analogues, Heterocycles, Nucleotides, Bases & Related Reagents, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
Boiling Point: No Data Available
Applications: 5-epi Emtricitabine is an epimer of Emtricitabine (E525000), a nucleoside reverse transcriptase inhibitor approved for treatment of human immunodeficiency virus (HIV) 1, and also has antagonistic activity against the hepatitis B virus. 5-epi Emtricitabine is also used as a reagent for the synthesis of β-L-(2R,5S)- and α-L-(2R,5R)-1,3-oxathiolane-pyrimidine and -purine nucleosides as potential HIV agents.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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