Catalogue number: E100500
Chemical name: E-64d
Synonyms: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; Aloxistatin; E 64c ethyl ester; E 64d; EP 453; EST; EST (pharmaceutical); Loxistatin; NSC 694281
CAS Number: 88321-09-9
Possible CAS #: NA
Molecular form.: C₁₇H₃₀N₂O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 342.43
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to interfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.
References: Wilcox, D. et al.: Biochem. J., 285, 495 (1992); McGowan, E.B. et al.: Biochem. Biophys. Res. Comm., 158, 432 (1989); Tsubokawa, T. et al.: J. Neurosci. Res., 84, 832 (2006);
Dangerous Goods Info: NA

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2.5mg $180.00
  Pack size Price(USD)
25mg $1440.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   Available in 2-3 weeks

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