E-64d

Catalogue number: E100500
Chemical name: E-64d
Synonyms: (2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-2-oxiranecarboxylic Acid Ethyl Ester; Aloxistatin; E 64c ethyl ester; E 64d; EP 453; EST; EST (pharmaceutical); Loxistatin; NSC 694281
CAS Number: 88321-09-9
Possible CAS #: NA
Molecular form.: C₁₇H₃₀N₂O₅
Appearance: No Data Available
Melting Point: No Data Available
Mol. Weight: 342.43
Storage: No Data Available
Solubility: No Data Available
Stability: No Data Available
Category: Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals,
Boiling Point: No Data Available
Applications: E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to interfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.
Dangerous Goods Info: NA
References:
Peer Review Product Citations:

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