E 64

Catalogue number: E100490
Chemical name: E 64
Synonyms: (2S,3S)-3-[[[(1S)-1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid; [2S-[2α,3β(R*)]]-3-[[[1-[[[4-[(Aminoiminomethyl)amino]butyl]amino]carbonyl]-3-methylbutyl]amino]carbonyl]oxiranecarboxylic Acid; Proteinase Inhibitor E 64; trans-Epoxysuccinyl-L-leucylamido-(4-guanidino)​Butane
CAS Number: 66701-25-5
Possible CAS #: NA
Molecular form.: C₁₅H₂₇N₅O₅
Appearance: White to Off-White Solid
Melting Point: >170°C (dec.)
Mol. Weight: 357.41
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: Aqueous Acid (Slightly), DMSO (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: E 64 is a caplain inhibitor used in the treatment of neurodegenerative diseases.
References: Schiefer, I. et al.: J. Med. Chem., 56, 6054 (2013); Song, J. et al.: Bioorg, Med. Chem. Lett., 23, 2801 (2013);
Dangerous Goods Info: NA

Order Product

  Pack size Price(USD)
5mg $125.00
100mg $1250.00
  Pack size Price(USD)
50mg $750.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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