Catalogue number: D535500
Chemical name: DOTA
Synonyms: 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic Acid; 1,4,7,10-Tetra(carboxymethyl)-1,4,7,10-tetraazacyclododecane; 1,4,7,10-Tetraazacyclododecane-N,N’,N’’,N’’’-tetraacetic acid; DOTA; NSC 681107; Tetraxetan
CAS Number: 60239-18-1
Possible CAS #: NA
Molecular form.: C₁₆H₂₈N₄O₈
Appearance: White to Off-White Solid
Melting Point: >225°C (dec.)
Mol. Weight: 404.42
Storage: Hygroscopic, Refrigerator, Under Inert Atmosphere
Solubility: Water (Slightly), Methanol (Slightly)
Stability: No Data Available
Category: Heterocycles, Labeling and Diagnostics Reagents, Pharmaceuticals, Intermediates & Fine Chemicals
Boiling Point: No Data Available
Applications: Bifunctional DOTA aconjugates to peptides and has become an established strategy for constructing target-specific metal containing agents including targeted MRI contrast agents and diagnostic and therapeutic radiopharmaceuticals.
Dangerous Goods Info: NA
References: Lewis, M., et al.: Bioconjug. Chem., 9, 72 (1998), Chappell, L., et al.: Bioorg. Med. Chem., 7, 2313 (1999), Prantner, A., et al.: Mol. Imaging, 2, 333 (2003), Allen, M., et al.: Chem. Biol., 11, 301 (2004), Weiner, R., et al.: BioDrugs, 19, 145 (2005), Breeman, W., et al.: Radionuclide Peptide Cancer Therapy, 119 (2006),
Peer Review Product Citations:

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