Dolutegravir Sodium Salt

Catalogue number: D528805
Chemical name: Dolutegravir Sodium Salt
Synonyms: Dolutegravir sodium; GSK 1349572A; N-[(2,4-Difluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-2H-pyrido[1’,2’:4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide Sodium Salt
CAS Number: 1051375-19-9
Possible CAS #: 1051375-16-6 free amine
Molecular form.: C₂₀H₁₈F₂N₃NaO₅
Appearance: Pale Yellow to Green Solid
Melting Point: >300ºC
Mol. Weight: 441.36
Storage: Hygroscopic, -20°C Freezer, Under inert atmosphere
Solubility: DMSO (Slightly, Heated)
Stability: No Data Available
Category: No Data Available
Boiling Point: No Data Available
Applications: Dolutegravir is a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.
Dangerous Goods Info: NA
References: Kobayashi, M. et al. Antimicrob Agents Chemother., 55, 813 (2011); Garrido, C. et al.: Antiviral, Res., 90, 164 (2011); Lenz, J.C.C. et al.: Exp. Opin. Invest. Drugs, 20, 537 (2011)
Peer Review Product Citations:

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  Pack size Price(USD)
2mg $140.00
5mg $230.00
25mg $510.00
  Pack size Price(USD)
2.5mg $175.00
10mg $350.00
50mg $760.00
Exact Weight Packaging ($75(USD) / Vial)
Inventory Status:   In Stock

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